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Elevated levels may indicate liver damage or disease. Higher than normal levels of direct bilirubin in your blood may indicate your liver isn't clearing bilirubin properly. Elevated levels of indirect bilirubin may indicate other problems.
- What causes elevated bilirubin with normal liver enzymes?
- Can bilirubin rise in non hepatic conditions?
- Can dehydration cause elevated bilirubin?
- What is considered mildly elevated bilirubin?
What causes elevated bilirubin with normal liver enzymes?
Gallstones may form if your body is already producing too much bilirubin due to a liver condition or if your liver's creating too much cholesterol. They can also be a complication of an infection of your bile ducts or from a blood disorder. Bilirubin builds up when your gallbladder's blocked and can't drain properly.
Can bilirubin rise in non hepatic conditions?
NON-HEPATIC CAUSES OF ABNORMALITY
Bilirubin levels are usually normal but up to fivefold increases are recognised.
Can dehydration cause elevated bilirubin?
Bilirubin levels may increase with stress, strain, dehydration, fasting, infection or exposure to cold. In many individuals, jaundice is only evident when one of these triggers raises the bilirubin levels.
What is considered mildly elevated bilirubin?
If total bilirubin is mildly elevated (usually <6 mg/dL) and less than 20% is conjugated (direct: total ratio <0.2), the most likely diagnoses are Gilbert syndrome or hemolysis. Gilbert syndrome affects ~5% of the population and causes mild hyperbilirubinemia because of impaired UDP-glucuronyltransferase.
