Can you change fretboard inlays?
One of the coolest and easiest mods to do on your guitar is replace the inlays. ... It's better to have a neck with no frets and (quite possibly, no finish) on it, but if you are replacing inlays on your existing neck, then go slow and be careful not to mess up your frets with the various tools you'll be using.
Can you remove fret inlays?
If you want to remove inlays, heat them with a soldering iron until the glue melts, then they should pop out. You're almost guaranteed to damage the inlays, but the board will remain intact. Obviously, only do this if you can route for and install the new inlays, then re-radius your fingerboard.