Are left handed guitars strung differently?
Simple, right? Aside from being a mirror image of their right handed counterparts, left handed guitars are exactly the same! The thickest string is still at the top, the order of the tuners doesn't change, the control layout is identical.
Can I string an acoustic guitar left handed?
Right hand acoustic guitars can be strung left handed. While the shape of an acoustic guitar is symmetrical (unless featuring a cutaway) attention should be paid to the nut and saddle which, depending on the guitar, in most cases will require replacing to ensure reliable intonation and playability.