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Gilbert's syndrome can be diagnosed using a blood test to measure the levels of bilirubin in your blood and a liver function test. When the liver is damaged, it releases enzymes into the blood. At the same time, levels of proteins that the liver produces to keep the body healthy begin to drop.
- Which bilirubin is elevated in Gilbert's syndrome?
- What medications should be avoided with Gilbert's syndrome?
- How high is bilirubin in Gilbert's syndrome?
- Can Gilbert's syndrome cause elevated liver enzymes?
Which bilirubin is elevated in Gilbert's syndrome?
Gilbert syndrome is characterized by elevated serum bilirubin, specifically unconjugated bilirubin due to a deficiency of bilirubin glucoronidation (11).
What medications should be avoided with Gilbert's syndrome?
Gilbert's syndrome: things to avoid
- Atazanavir (Reyataz®) and indinavir (Crixivan®), which are both used to treat HIV infection.
- Gemfibrozil (Lopid®), a drug used to lower cholesterol.
- Irinotecan (Camptosar®), a drug used to treat advanced bowel cancer.
How high is bilirubin in Gilbert's syndrome?
In Gilbert syndrome, the degree of hyperbilirubinemia is typically less than 5 mg/dL and the conjugated bilirubin is typically less than 20% of the total bilirubin fraction. The Medicare midpoint reimbursement for a total and direct serum bilirubin is $9.25 for each.
Can Gilbert's syndrome cause elevated liver enzymes?
Individuals with Gilbert syndrome have elevated levels of bilirubin (hyperbilirubinemia), because they have a reduced level of a specific liver enzyme required for elimination of bilirubin.
