Can anybody help me meaning?
Can anybody help me? What's the difference? Both sentences mean pretty much the same thing - you need help. With sentence number 2, the speaker is more eager for help - perhaps he/she has already been turned down by someone, or another person tried to help but was unable to do so.
Can anybody or somebody help me?
Someone vs. Somebody. Anyone is a pronoun that means "any person." So if you would like help from a person and you don't care who that person is, then you would like help from anyone. ... Anybody is a pronoun that is interchangeable with anyone.