It's either a result of the pickups you're using, interference getting picked up by your guitar or a grounding issue. ... Note: it's normal for an amp to hum when a lead is plugged in but not plugged into a guitar. So if you have your lead lying on the ground while plugged into your amp, don't stress if you hear noise.
Why is my amp making a buzzing noise?
A healthy amp is likely to make some sort of noise when idle. ... Poor quality pedal boards, FX units or even guitars will feed noise into the amp that will be exponentially amplified. If the AC supply is poor or your outlet is not earthed well enough then it can create a humming or buzzing sound.
How do I get my amp to stop buzzing?
Start off really simple and listen, then add another piece and listen. Start off with your guitar plugged directly into your amp with your settings where you would normally have them. Make sure AC adapters are far away from your cables. They make noise, and you can hear it just by moving it over your cables.